Papain is an enzyme found naturally in the fruit of the papaya tree (Carica papaya). This enzyme helps break down protein, the process of making it ideal as a meat tenderizer. Papaya has long been used in folk medicine to reduce pain, swelling, and inflammation. Others believe that it can improve digestive health and treat some common infections. You can get papain from eating raw papaya. Papain is also available in the form of topical, chewable tablets and capsules. Alternatively, you can also buy papain-only supplements or supplements that combine papain with other enzymes, such as bromelain.
1. How does the enzyme Papain work?
✅ Papaya is believed to contain several proteolytic enzymes, including papain, chymopapain A, chymopapain B, and peptidase A. However, the most famous and the most famous enzyme is the papain found in immature fruit of plants papaya. Papain helps break the link between amino acids, the building block of protein. Like all proteolytic enzymes, it breaks down long-chain-like protein molecules into shorter segments, called peptides, then into their basic components, called amino acids. This makes the papain enzyme has analgesic, inflammatory, swollen, and some other diseases.
2. Papain health benefits
2.1 Relieves pain and ANTI-inflammation
✅ Papain has been shown to reduce inflammation in patients with asthma, arthritis, and other inflammatory conditions. A study published in 2013 in the Journal of Nutrition Assessment indicated that proteolytic enzymes, including papain and trypsin, can disrupt pathogenic immune complexes and even prevent the formation of them from the beginning. This means that papain can prevent infection from occurring.
✅ Analgesia: Several studies have shown that papaya enzymes have analgesic effects in a number of areas, including intense exercise-induced muscle pain, sore throat, and shingles-related pain.
- Papain can help relieve sore throat symptoms, such as swelling, pain, and redness. Based on a study of 100 people with sore throat or tonsillitis, lozenges contain 2 milligrams (mg) of papain, 5 mg of lysozyme, and 200 international units (IU) of bacitracin, which help reduce symptoms of sore throat better than placebo.
- A study published in the Journal of Sports Science found that supplementing with protease containing papaya enzyme could help reduce running muscle pain. Participants used protease tablets containing 50 milligrams of papain, in addition to other enzymes such as bromelain, trypsin, amylase, and lipase. After taking 2 capsules 4 times a day for 4 days, runners found superior recovery and reduced muscle soreness compared to the placebo group.
2.2 Support wound healing
✅ Topical papain enzyme products are often used for their wound-healing effects. There are preliminary studies supporting the papaya enzyme’s ability to aid wound healing. A 2010 animal study conducted in Malaysia showed that papain-based wound cleaners help reduce wounds, promote collagen deposition, and show antibacterial properties. However, the FDA warns consumers about possible allergic reactions when applying this enzyme. You should talk to your doctor about personal risk for allergies before use.
2.3 Supports digestive health
✅ Papain supplements are thought to help improve gastrointestinal dysfunction and common digestive problems like bloating and constipation. Like other protease enzymes, studies show that papain helps the body break down protein foods, like animal meat. And this enzyme does not need the presence of acid to do its job. This means that even people with low stomach acid, who often have difficulty breaking down and digesting certain types of meat, can benefit from papain supplements. According to a 2013 study, a whole papaya preparation called Caricol significantly improved constipation and flatulence in people with chronic digestive disorders.
2.4 Reduce symptoms of shingles
✅ There is growing evidence that papain can help treat shingles (herpes zoster), the often painful reactivation of chickenpox virus often seen in older adults. Proteolytic enzymes such as papain can help with shingles symptoms such as pain, skin damage, and neuropathy. A 2016 review in the Journal of Immunology supported these findings, showing that papain inhibits an inflammatory protein, called transforming growth factor-beta (TGF-β1), which could increase the outbreak of the onset of shingles. By blocking TGF-β1, pain, severity, and outbreak time can be greatly reduced. According to a 1995 Controlled Study, of 192 people with shingles, a protein-proteolytic enzyme preparation is effective in treating shingles symptoms such as acyclovir antiviral drugs. However, more evidence is needed to confirm these findings.
3. Notes when using Papain
- Papain can irritate the throat and stomach. In excessive doses, papain can cause severe throat damage. Serious allergic reactions may also occur. People who are allergic to figs and kiwi may also be allergic to papain.
- Pregnant and lactating women: taking papain during pregnancy may not be safe. Experts fear the drug could cause birth defects or miscarriage. There is not enough information about the safety of using papain during breastfeeding. Therefore, papain should not be used if you are pregnant or breastfeeding.
- Bleeding disorders: papain may increase the risk of bleeding in people with blood clotting disorders or taking anti-coagulants such as warfarin. Because of this, papain may increase the risk of bleeding during surgery. Stop taking papain 2 weeks before you have surgery.
4. Recommended for you :
🎁 NOW Supplements, Papaya Enzyme with Mint and Chlorophyll, Digestive Support
✅ Since 1968 NOW has been a leader in the natural products industry. Even when healthy foods and natural supplements weren’t mainstream, we’ve never wavered from our mission – to provide value in products and services that Empower people to lead healthier lives.
✅ Digestive enzymes are essential to the body’s absorption and full use of food. The capacity of the body to make enzymes diminishes with age, and therefore the efficiency of digestion declines. NOW Papaya Enzyme Lozenges have a refreshing taste and support digestion when taken after meals. Their lozenges are made with whole, unripe, spray-dried papaya powder, and have 40 mg of papaya per lozenge. In addition, protease, lipase, and cellulase have been included for a full spectrum of enzymatic activity. This tablet is also useful as a mint breath freshener. Directions: As a dietary supplement, adults chew or dissolve 2 lozenges in the mouth following meals or as needed. For children (over 4), chew or dissolve 1 lozenge in the mouth following meals or as needed. Safety Information: Consult physician if pregnant/nursing.