Mannose is a simple sugar, called a monosaccharide. Some other names of mannose include D-mannose, carubinose, and seminose. They are produced in the human body from glucose or converted into glucose when consumed in fruits and vegetables. Structurally, D-mannose is similar to glucose. However, it is absorbed at a slower rate in the digestive tract. It has a lower glycemic index than glucose. This is because, after consumption, it needs to be converted into fructose and then glucose, thus reducing the insulin response and impact on your blood sugar. In addition, recent studies have shown D-mannose to have potential in cancer prevention and many health benefits.
1. Top 4 D-mannose benefits
1.1 D-mannose benefits: Prevent urinary tract infection
✅ D-mannose is thought to prevent certain bacteria from attaching to the walls of the urinary tract. The mannose receptors are part of the protective layer found on cells lining the urinary tract. These receptors can bind to E. coli and get washed away during urination, thus preventing both the adhesion and invasion of urinary bacteria. A 2014 study reported in the British Urology Journal found that D-mannose (the active ingredient concentrated in cranberry juice) is as effective as antibiotics to prevent recurrent urinary tract infections. have side effects.
1.2 D-mannose benefits: Treatment of type 1 diabetes
✅ The researchers were surprised to find that D-mannose was able to prevent and inhibit type 1 diabetes, a condition where the body does not produce insulin – a hormone needed to bring glucose from the bloodstream into cells of the body.
✅ A study of mice with autoimmune diabetes found that D-mannose could inhibit type 1 diabetes. In this study, they added a small amount of D-mannose in the drinking water of diabetic mice before they developed any symptoms. This prevented the development of diabetes in these mice, while the water-drinking mice were frequently ill. The group then showed that D-mannose increased the production of regulatory T cells, a group of cells that regulate the immune system and prevent autoimmune disease. D-mannose, therefore, suppresses inflammation in rats and prevents the development of autoimmune diseases like diabetes.
✅ To conclude, this study suggests that D-mannose is a ‘healthy’ or ‘good’ sugar that may be a safe dietary supplement. However, such promising studies need to be done in humans.
1.3 D-mannose benefits: Works as a prebiotic
✅ Prebiotics help nourish probiotics in your gut and amplify their health-promoting properties. Mannose is known to act as a prebiotic that stimulates the growth of good bacteria in your gut. Studies show that mannose exhibits both anti-inflammatory and immunomodulatory properties. When D-mannose is used in combination with probiotics, they can restore the composition and amount of beneficial microorganisms in the gut.
1.4 D-mannose benefits: Prevention of cancer
✅ Like healthy cells, the main source of energy for cancer cells is glucose. Therefore, cutting glucose to destroy tumor cells is a useful way to limit the growth of cancer cells but in fact, this is a challenge. Because the body tightly controls the level of glucose in the body because all cells need glucose, the body cannot eliminate it completely from the system, according to Medical News. When mannose enters cells, it slows down glucose metabolism, according to Medical News Today.
✅ To study its anti-cancer properties, scientists added this sugar to the drinking water of mice with pancreatic cancer, skin cancer, or lung cancer. They found that these mice had no side effects but the tumor growth was significantly slowed down, said Professor Kevin Ryan, of the Beatson Cancer Research Institute (UK), the lead author of the study on Medical News Today. In the same study, experts found that the amount of mannose needed to reduce glucose levels just enough to slow tumor growth in mice, but not so much that normal tissues were affected. This is an initial study, but hopefully, in the future, Mannose could be granted to cancer patients to enhance the effectiveness of chemotherapy without harming their overall health, Professor Kevin Ryan announced.
2. Foods that contain mannose
Natural d-mannose is often rich in some foods, especially fruits. Here are some of the top D-mannose foods that you can easily add to your diet:
- Cranberries
- Oranges
- Apples
- Peaches
- Blueberries
- Mangos
- Gooseberries
- Black currants
- Red currants
- Tomatoes
- Seaweed
- Aloe vera
- Green beans
- Eggplant
- Broccoli
- Cabbage
- Fenugreek seeds
- Kidney beans
- Turnips
- Cayenne pepper
3. Notes when using Mannose
- D-mannose supplements can easily be found online and in some health food stores. They are available in capsule and powder form. Each capsule usually weighs 500 mg, so you should only use 2-4 capsules a day when treating urinary tract infections.
- D-mannose powder is also another popular option because it helps you control your dosage, and it easily dissolves in water. However, it is best to make sure to use the amount that the manufacturer requires.
- Pregnant and lactating women should consult a physician before use.
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✅ D-mannose is a naturally occurring simple sugar that your body utilizes to help cleanse the urinary tract and maintain a healthy bladder lining. Its metabolized only in small amounts, with excess amounts rapidly excreted in the urine, so it won’t interfere with healthy blood sugar regulation. Clinical studies have demonstrated that, when taken regularly, D-mannose promotes normal urinary tract function by cleansing and maintaining the health of the bladder lining. Directions: As a dietary supplement, take 3 capsules 1 to 3 times daily. Take with water or unsweetened juice, such as unsweetened cranberry juice. Safety Information: For adults only. Keep out of reach of children. Consult physician if pregnant/nursing.
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